Philippe Lehert Selected Research

2- (2,6- dimethyl- 4- (3- (4- (methylthio)phenyl)- 3- oxo- 1- propenyl)phenoxyl)- 2- methylpropanoic acid

1/2016

Elafibranor, an Agonist of the Peroxisome Proliferator-Activated Receptor-α and -δ, Induces Resolution of Nonalcoholic Steatohepatitis Without Fibrosis Worsening.

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Philippe Lehert Research Topics

Disease

13	Alcoholism (Alcohol Abuse) 03/2012 - 10/2002
11	Type 2 Diabetes Mellitus (MODY) 10/2022 - 12/2002
5	Disorders of Excessive Somnolence (Hypersomnia) 11/2023 - 04/2008
5	Narcolepsy 01/2023 - 04/2008
5	Cataplexy 01/2023 - 04/2008
4	Weight Gain 01/2018 - 12/2002
3	Sleepiness 11/2023 - 04/2008
3	Abdominal Pain (Pain, Abdominal) 01/2021 - 12/2002
3	Body Weight (Weight, Body) 01/2018 - 12/2002
2	Overweight 01/2023 - 07/2018
2	Headache (Headaches) 01/2023 - 01/2017
2	Sleep Initiation and Maintenance Disorders (Insomnia) 01/2023 - 09/2018
2	Anaphylaxis (Anaphylactic Shock) 01/2023 - 07/2018
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 01/2016
2	Charcot-Marie-Tooth Disease (Peroneal Muscular Atrophy) 07/2016 - 12/2014
2	Diarrhea 09/2010 - 12/2002
2	Substance-Related Disorders (Drug Abuse) 09/2009 - 11/2004
1	Obstructive Sleep Apnea 11/2023
1	Bronchopulmonary Dysplasia 08/2023
1	Ulcerative Colitis 01/2023
1	Fatigue 01/2022
1	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 01/2021
1	Multiple Sclerosis 01/2020
1	Infertility (Sterility) 11/2019
1	Vitamin D Deficiency 01/2018
1	Graft vs Host Disease (Graft-Versus-Host Disease) 01/2017
1	Virus Diseases (Viral Diseases) 01/2017
1	Nausea 01/2017
1	Hypertension (High Blood Pressure) 10/2016
1	Insulin Resistance 01/2016
1	Non-alcoholic Fatty Liver Disease 01/2016
1	Liver Cirrhosis (Hepatic Cirrhosis) 01/2016
1	Inflammation (Inflammations) 01/2016
1	Fibrosis (Cirrhosis) 01/2016
1	Disease Progression 06/2015
1	Substance Withdrawal Syndrome (Withdrawal Symptoms) 11/2013
1	Surgical Wound Infection 01/2013
1	Intermittent Claudication 12/2012
1	Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left) 08/2012
1	Goiter 06/2012
1	Euthyroid Goiter 06/2012
1	Dehydration (Water Stress) 09/2011
1	Gastroenteritis 09/2011
1	Vitamin B 12 Deficiency (Vitamin B12 Deficiency) 05/2010

Drug/Important Bio-Agent (IBA)

14	Acamprosate (Campral)FDA Link 09/2018 - 10/2002
12	Metformin (Glucophage)FDA LinkGeneric 10/2022 - 12/2002
11	Insulin (Novolin)FDA Link 01/2022 - 12/2002
8	pitolisantIBA 11/2023 - 04/2008
4	Naltrexone (ReVia)FDA LinkGeneric 07/2016 - 11/2004
3	Histamine H3 Receptors (Histamine H3 Receptor)IBA 01/2023 - 11/2013
3	Modafinil (Provigil)FDA Link 01/2020 - 11/2013
3	LipidsIBA 01/2016 - 12/2002
2	Sodium Oxybate (gamma Hydroxybutyrate)FDA Link 01/2023 - 12/2018
2	Epinephrine (Adrenaline)FDA LinkGeneric 01/2023 - 07/2018
2	Hormones (Hormone)IBA 11/2019 - 01/2007
2	HDL CholesterolIBA 10/2016 - 05/2004
2	Sorbitol (Yal)FDA Link 07/2016 - 12/2014
2	Baclofen FDA LinkGeneric 07/2016 - 12/2014
2	Glucose (Dextrose)FDA LinkGeneric 01/2016 - 12/2002
2	Fosinopril (Monopril)FDA LinkGeneric 08/2012 - 12/2007
2	LDL CholesterolIBA 05/2004 - 12/2002
1	Hydrocortisone (Cortisol)FDA LinkGeneric 08/2023
1	Arginine (L-Arginine)FDA Link 10/2022
1	TroponinIBA 01/2022
1	Troponin IIBA 01/2022
1	pinaveriumIBA 01/2021
1	Parasympatholytics (Antispasmodics)IBA 01/2021
1	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2021
1	Interferon-betaIBA 01/2020
1	Methylmalonic AcidIBA 01/2018
1	Vitamin D FDA LinkGeneric 01/2018
1	hydroxide ionIBA 01/2018
1	inolimomabIBA 01/2017
1	SteroidsIBA 01/2017
1	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2016
1	EnzymesIBA 01/2016
1	2- (2,6- dimethyl- 4- (3- (4- (methylthio)phenyl)- 3- oxo- 1- propenyl)phenoxyl)- 2- methylpropanoic acidIBA 01/2016
1	CreatinineIBA 01/2016
1	Ascorbic Acid (Vitamin C)FDA LinkGeneric 06/2015
1	Amphetamine (Amfetamine)FDA LinkGeneric 11/2013
1	CollagenIBA 01/2013
1	Gentamicins (Gentamicin)FDA LinkGeneric 01/2013
1	Nafronyl (Naftidrofuryl)IBA 12/2012
1	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 08/2012
1	IodineIBA 06/2012
1	racecadotril (ecadotril)IBA 09/2011
1	SolutionsIBA 09/2011
1	VitaminsIBA 05/2010
1	HomocysteineIBA 05/2010
1	Folic Acid (Vitamin M)FDA LinkGeneric 05/2010
1	Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric 05/2010

Therapy/Procedure

5	Therapeutics 11/2023 - 12/2002
2	Intramuscular Injections 01/2023 - 07/2018
2	Glycemic Control 03/2009 - 12/2002
1	Continuous Positive Airway Pressure 11/2023
1	Subcutaneous Injections 01/2023
1	Fecal Microbiota Transplantation 01/2023
1	Renal Dialysis (Hemodialysis) 08/2012
1	Fluid Therapy (Oral Rehydration Therapy) 09/2011
1	Activities of Daily Living (ADL) 03/2010